A non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and COX-2

Indomethacin – 1 g

Brand:
Cayman
CAS:
53-86-1
Storage:
22
UN-No:
De Minimis - 2811 / 6.1

Indomethacin is a non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and COX-2, respectively).{1286} It reduces filter paper-disc induced growth of granulation tissue, a marker of inflammation, in chick chorioallantoic membranes.{37630} Indomethacin reduces ocular inflammation induced by bovine serum in rabbits.{37631} It also reduces paw edema in a rat model of carrageenan-induced inflammation.{37632}  

 

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SKU: 70270 - 1 g Category:

Description

A non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and COX-2, respectively); reduces filter paper-disc induced growth of granulation tissue in chick chorioallantoic membranes; reduces ocular inflammation induced by bovine serum in rabbits; reduces paw edema in a rat model of carrageenan-induced inflammation

Formal name: 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid

Synonyms: 

Molecular weight: 357.8

CAS: 53-86-1

Purity: ≥99%

Formulation: A crystalline solid

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