2-Linoleoyl Glycerol – 10 mg

Brand:
Cayman
CAS:
3443-82-1
Storage:
-80
UN-No:
Excepted Quantity - 1648 / 3

2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.{4614,5306} The congener of 2-AG in which a linoleoyl group replaces the arachidonoyl group is 2-linoleoyl glycerol (2-LG), and this compound also appears in vivo in conjunction with 2-AG.{9610} Although the intrinsic activity of 2-LG is low, it potentiates the activity of other endocannabinoids, including 2-AG. This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.  

 

Available on backorder

SKU: 62260 - 10 mg Category:

Description

A congener of 2-AG in which a linoleoyl group replaces the arachidonoyl group that potentiates the activity of other endocannabinoids, including 2-AG; this “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to rapidly reduce endocannabinoid levels following release


Formal name: 9Z,12Z-octadecadienoic acid, 2-glyceryl ester

Synonyms:  2-LG

Molecular weight: 354.5

CAS: 3443-82-1

Purity: ≥95% (as a 9:1 mixture of the 2-LG and 1-LG)

Formulation: A solution in acetonitrile