Hexanolamino PAF C-16 is a PAF analog with mixed PAF receptor agonist/antagonist properties. In human monocyte-derived macrophages

Hexanolamino PAF C-16 – 25 mg

Brand:
Cayman
CAS:
137566-83-7
Storage:
-20
UN-No:
Non-Hazardous - /

Hexanolamino PAF C-16 is a PAF analog with mixed agonist/antagonist properties. In human monocyte-derived macrophages, it is an antagonist which inhibits the production of reactive oxygen species in response to PAF C-16.{367} On the other hand, in rabbit platelets and guinea pig macrophages, hexanolamino PAF C-16 is a partial agonist, and in guinea pig platelets it is a full agonist.{3786}  

 

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Description

Hexanolamino PAF C-16 is a PAF analog with mixed PAF receptor agonist/antagonist properties. In human monocyte-derived macrophages, it is an antagonist which inhibits the production of reactive oxygen species in response to PAF C-16.{367} On the other hand, in rabbit platelets and guinea pig macrophages, hexanolamino PAF C-16 is a partial agonist, and in guinea pig platelets it is a full agonist.{3786}

Formal name: 1-O-hexadecyl-2-O-acetyl-sn-glyceryl-3-phosphoryl(N,N,N-trimethyl)hexanolamine

Synonyms: 

Molecular weight: 579.8

CAS: 137566-83-7

Purity: ≥98%

Formulation: A lyophilized powder

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