Description
PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and ‘de novo’ pathways.{939} It is a potent mediator of neutrophil migration,{1437} and the production of reactive oxygen species, and IL-6 in human macrophages.{367,2296} It is a more potent mediator of platelet aggregation than PAF C-18.{3786} Pathological processes involving PAF include necrotizing enterocolitis,{5841} inflammation, asthma, and allergy.{303}
Formal name: 1-O-hexadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine
Synonyms: Platelet-activating Factor C-16
Molecular weight: 523.7
CAS: 74389-68-7
Purity: ≥98%
Formulation: A lyophilized powder