Description
A major LO product in PMA-treated murine epidermis
Formal name: 8S-hydroxy-5Z,9E,11Z,14Z-eicosatetraenoic acid
Synonyms:
Molecular weight: 320.5
CAS: 98462-03-4
Purity: ≥98%
Formulation: A solution in ethanol
8(S)-HETE – 100 µg
Brand:
Cayman
CAS:
98462-03-4
Storage:
-20
UN-No:
De Minimis - 1170 / 3
8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis.{172} It activates mouse keratinocyte protein kinase C with an IC50 of 100 µM.{2787} 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 µM.{6788} Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.{30214}
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