An autoxidation product of DHA in vitro that can also be produced from incubation of DHA with rat liver

(±)4-HDHA – 50 µg

Brand:
Cayman
CAS:
90906-40-4
Storage:
-20
UN-No:
De Minimis - 1170 / 3

(±)4-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.{7479,7491} It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.{7480,7490,7492} Enzymatic transformation of DHA by RBL-1 cells also produces 4-HDHA.{7515} However, the enzymatic product is most likely the S-isomer. (±)4-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.  

 

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SKU: 33200 - 50 µg Category:

Description

An autoxidation product of DHA in vitro that can also be produced from incubation of DHA with rat liver, brain, and intestinal microsomes and enzymatic transformation of DHA by RBL-1 cells; is a potential marker of oxidative stress in brain and retina where DHA is an abundant PUFA

Formal name: (±)4-hydroxy-5E,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid

Synonyms:  (±)4-HDoHE|4-hydroxy Docosahexaenoic Acid

Molecular weight: 344.5

CAS: 90906-40-4

Purity: ≥95%

Formulation: A solution in ethanol

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