A diterpene alkaloid with diverse biological activities; inhibits binding of α-bungarotoxin to rat neuronal α7 nAChRs (IC50 = 19 µM); repellent against adult red flour beetles in a filter paper assay at 3 mg/ml; lowers systolic blood pressure in a rat model of left renal artery ligation-induced hypertension at 75 mg/kg

Delsoline – 1 mg

Brand:
Cayman
CAS:
509-18-2
Storage:
-20
UN-No:
Non-Hazardous - /

Delsoline is a diterpene alkaloid that has been found in Delphinium and has diverse biological activities.{61115,61116,61117} It inhibits binding of α-bungarotoxin (Item No. 16385) to rat neuronal α7 nicotinic acetylcholine receptors (nAChRs; IC50 = 19 µM).{61115} Delsoline (3 mg/ml) is repellent against adult red flour beetles (T. castaneum) in a filter paper assay.{61116} In vivo, delsoline (75 mg/kg) lowers systolic blood pressure in a rat model of left renal artery ligation-induced hypertension.{61117}  

 

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SKU: 31748 - 1 mg Category:

Description

A diterpene alkaloid with diverse biological activities; inhibits binding of α-bungarotoxin to rat neuronal α7 nAChRs (IC50 = 19 µM); repellent against adult red flour beetles in a filter paper assay at 3 mg/ml; lowers systolic blood pressure in a rat model of left renal artery ligation-induced hypertension at 75 mg/kg

Formal name: (1α,6β,14α,16β)-20-ethyl-6,14,16-trimethoxy-4-(methoxymethyl)-aconitane-1,7,8-triol

Synonyms:  Acomonine

Molecular weight: 467.6

CAS: 509-18-2

Purity: ≥95%

Formulation: A solid

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