Description
A derivative of gemcitabine; in nanoparticle form it has synergistic effects when used in combination with cisplatin nanoparticles in vitro at a one-to-one molar ratio (IC50s = 5.95 and 34.8 for the nanoparticle combination and gemcitabine monophosphate alone, respectively); in nanoparticle form it inhibits tumor growth and increases apoptosis in a stroma-rich mouse xenograft model
Formal name: 2′-deoxy-2′,2′-difluoro-5′-cytidylic acid
Synonyms:
Molecular weight: 343.2
CAS: 116371-67-6
Purity: ≥95%
Formulation: A crystalline solid
