Description
An atypical antipsychotic and dopamine D2 receptor antagonist (Ki = 0.2 µM); selective for the D2 receptor over a panel of 33 receptors, neurotransmitter transporters, and ion channels at 10 µM but does inhibit the σ receptor (Ki = 0.065 µM); increases striatal DOPAC and HVA levels in rats from 2-20 µmol/kg; inhibits apomorphine-induced stereotypy and hyperactivity in rats (ED50s = 5.6 and 0.8 µmol/kg, respectively)
Formal name: 3-bromo-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2,6-dimethoxy-benzamide, monohydrochloride
Synonyms:
Molecular weight: 407.7
CAS: 73220-03-8
Purity: ≥98%
Formulation: A crystalline solid
