An anticonvulsant; protects against MES-

Valrocemide – 100 mg

Brand:
Cayman
CAS:
92262-58-3
Storage:
-20
UN-No:
Non-Hazardous - /

Valrocemide is an anticonvulsant and a derivative of valproic acid (Item No. 13033).{52702} In vivo, valrocemide protects against seizures induced by maximal electroshock (MES), pentylenetetrazole (PTZ; Item No. 18682), picrotoxin (Item No. 20771), or bicuculline (Item No. 11727) in mice (ED50s = 151, 132, 275, and 248 mg/kg, respectively). It prevents sound-induced seizures in Frings audiogenic-sensitive mice (ED50 = 52 mg/kg) and MES-induced seizures in rats (ED50 = 73 mg/kg). Valrocemide also prevents seizures in corneally kindled rats (ED50 = 161 mg/kg).  

 

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SKU: 30909 - 100 mg Category:

Description

An anticonvulsant; protects against MES-, PTZ-, picrotoxin-, or bicuculline-induced seizures in mice (ED50s = 151, 132, 275, and 248 mg/kg, respectively); prevents sound-induced seizures in Frings audiogenic-sensitive mice (ED50 = 52 mg/kg) and MES-induced seizures in rats (ED50 = 73 mg/kg); prevents seizures in corneally kindled rats (ED50 = 161 mg/kg)

Formal name: N-(2-amino-2-oxoethyl)-2-propyl-pentanamide

Synonyms:  N-Valproyl glycinamide|TV1901|VGD

Molecular weight: 200.3

CAS: 92262-58-3

Purity: ≥95%

Formulation: A solid

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