A tyrosinase inhibitor (Ki = 0.21 μM in an enzyme assay using L-DOPA as a substrate) and building block; increases the susceptibility of SK-MEL-188 melanoma cells in melanogenesis-inducing conditions to γ-radiation-induced cytotoxicity at 0.01 μM; has been used as a precursor in the synthesis of compounds with antibacterial and antifungal activities; used as a genetic marker for taste

N-Phenylthiourea – 250 g

Brand:
Cayman
CAS:
103-85-5
Storage:
-20
UN-No:
Limited Quantity - 2811 / 6.1

N-Phenylthiourea is a tyrosinase inhibitor (Ki = 0.21 μM in an enzyme assay using L-DOPA as a substrate) and building block.{52758,52759} It increases the susceptibility of SK-MEL-188 melanoma cells in melanogenesis-inducing conditions to γ-radiation-induced cytotoxicity when used at a concentration of 0.01 μM.{52760} N-Phenylthiourea has been used as a precursor in the synthesis of compounds with antibacterial and antifungal activities.{52759} It has also been used as a genetic marker for taste because only some people detect it as a bitter taste.{22286}  

 

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SKU: 30855 - 250 g Category:

Description

A tyrosinase inhibitor (Ki = 0.21 μM in an enzyme assay using L-DOPA as a substrate) and building block; increases the susceptibility of SK-MEL-188 melanoma cells in melanogenesis-inducing conditions to γ-radiation-induced cytotoxicity at 0.01 μM; has been used as a precursor in the synthesis of compounds with antibacterial and antifungal activities; used as a genetic marker for taste

Formal name: N-phenyl-thiourea

Synonyms:  1-Phenyl-2-thiourea|NSC 5779|Phenylthiocarbamide|Phenylthiourea|PTC|PTU

Molecular weight: 152.2

CAS: 103-85-5

Purity: ≥98%

Formulation: A crystalline solid

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