An alkaloid with diverse biological activities; active against P. falciparum (IC50 = 1.026 µg/ml); inhibits SARS-CoV viral infection in Vero cells (EC50 = 15.7 µM); inhibits migration of A549 NSCLC and U373 MG glioblastoma cells at 5 µM; increases survival and reduces virus-induced paralysis in a mouse model of enterovirus 71 infection at 0.4 mg/kg

Lycorine – 5 mg

Brand:
Cayman
CAS:
476-28-8
Storage:
-20
UN-No:
- 2811 / 6.1

Lycorine is an alkaloid that has been found in Amaryllidaceae and has diverse biological activities.{57080,57081,57082,57083} It is active against P. falciparum (IC50 = 1.026 µg/ml).{57080} Lycorine inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) viral infection in Vero cells (EC50 = 15.7 µM).{57081} It inhibits migration of A549 non-small cell lung cancer (NSCLC) and U373 MG glioblastoma cells when used at a concentration of 5 µM.{57082} Lycorine (0.4 mg/kg) increases survival and reduces virus-induced paralysis in a mouse model of enterovirus 71 infection.{57083}  

 

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SKU: 30650 - 5 mg Category:

Description

An alkaloid with diverse biological activities; active against P. falciparum (IC50 = 1.026 µg/ml); inhibits SARS-CoV viral infection in Vero cells (EC50 = 15.7 µM); inhibits migration of A549 NSCLC and U373 MG glioblastoma cells at 5 µM; increases survival and reduces virus-induced paralysis in a mouse model of enterovirus 71 infection at 0.4 mg/kg

Formal name: (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol

Synonyms:  Narcissin

Molecular weight: 287.3

CAS: 476-28-8

Purity: ≥95%

Formulation: A crystalline solid

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