A flavonoid with diverse biological activities; active against P. falciparum in vitro (IC50 = 23 µM); inhibits the cytopathic effect of EV71 in Vero cells (EC50 = 0.68 µM); increases survival in a neonatal mouse model of EV71 infection at 1 and 5 mg/kg; increases proliferation and osteogenic differentiation of isolated BMSCs; prevents estrogen deficiency-induced bone loss in ovariectomized mice

Chrysosplenetin – 5 mg

Brand:
Cayman
CAS:
603-56-5
Storage:
-20
UN-No:
Non-Hazardous - /

Chrysosplenetin is a flavonoid that has been found in A. annua and has diverse biological activities.{57215,57216,57217} It is active against P. falciparum in vitro (IC50 = 23 µM).{57215} Chrysosplenetin inhibits the cytopathic effect of enterovirus 71 (EV71) in Vero cells (EC50 = 0.68 µM) and increases survival in a neonatal mouse model of EV71 infection when administered at doses of 1 and 5 mg/kg.{57216} It also increases proliferation and osteogenic differentiation of isolated human bone marrow stromal cells (BMSCs) and prevents estrogen deficiency-induced bone loss in ovariectomized mice.{57217}  

 

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SKU: 30625 - 5 mg Category:

Description

A flavonoid with diverse biological activities; active against P. falciparum in vitro (IC50 = 23 µM); inhibits the cytopathic effect of EV71 in Vero cells (EC50 = 0.68 µM); increases survival in a neonatal mouse model of EV71 infection at 1 and 5 mg/kg; increases proliferation and osteogenic differentiation of isolated BMSCs; prevents estrogen deficiency-induced bone loss in ovariectomized mice

Formal name: 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one

Synonyms:  Chrysosplenol B|Chrysosptertin B|EMD 20940|Polycladin

Molecular weight: 374.3

CAS: 603-56-5

Purity: ≥98%

Formulation: A crystalline solid

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