A capsid-binding antiviral agent; inhibits the cytopathic effects of HRV2 and HRV14 in HeLa Ohio cells (EC50s = 1 and 5 ng/ml

Vapendavir – 5 mg

Brand:
Cayman
CAS:
439085-51-5
Storage:
-20
UN-No:
Non-Hazardous - /

Vapendavir is a capsid-binding antiviral agent.{52755,52756} It binds to a pocket in the human rhinovirus (HRV) strain HRV2 VP1 capsid protein and inhibits the cytopathic effects of HRV2 and HRV14 in HeLa Ohio cells (EC50s = 1 and 5 ng/ml, respectively), as well as in a panel of 39 HRV clinical isolates (median EC50 = 7.3 ng/ml).{52755} Vapendavir inhibits replication in a panel of 21 enterovirus 71 (EV71) isolates with an average EC50 value of 0.7 μM.{52756}  

 

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SKU: 30546 - 5 mg Category:

Description

A capsid-binding antiviral agent; inhibits the cytopathic effects of HRV2 and HRV14 in HeLa Ohio cells (EC50s = 1 and 5 ng/ml, respectively), as well as in a panel of 39 HRV clinical isolates (median EC50 = 7.3 ng/ml); inhibits replication in a panel of 21 EV71 isolates (average EC50 = 0.7 µM)

Formal name: 3-ethoxy-6-[2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]-1,2-benzisoxazole

Synonyms:  BTA798

Molecular weight: 382.5

CAS: 439085-51-5

Purity: ≥95%

Formulation: A crystalline solid

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