A radi; oprotective agent; decreases radiation-induced lethality without affecting radiation-induced tumor regression in an Ehrlich murine spontaneous adenocarcinoma model at 300 mg/kg; prevents radiation-induced damage of intestinal

DMA (hydrochloride) – 1 mg

Brand:
Cayman
CAS:
2095832-33-8
Storage:
-20
UN-No:
Non-Hazardous - /

DMA is a bisbenzimidazole radioprotective agent.{49648,49649} In vivo, DMA (300 mg/kg) decreases radiation-induced lethality without affecting radiation-induced tumor regression in an Ehrlich murine spontaneous adenocarcinoma model.{49648} It prevents radiation-induced damage of intestinal, hepatic, and splenic tissues, increases in splenic malondialdehyde (MDA) production, and decreases in splenic superoxide dismutase (SOD) activity in a B16/F10 murine melanoma model when administered at a dose of 50 mg/kg.{49649}  

 

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SKU: 30416 - 1 mg Category:

Description

A radi; oprotective agent; decreases radiation-induced lethality without affecting radiation-induced tumor regression in an Ehrlich murine spontaneous adenocarcinoma model at 300 mg/kg; prevents radiation-induced damage of intestinal, hepatic, and splenic tissues, increases in splenic MDA production, and decreases in splenic SOD activity in a B16/F10 murine melanoma model at 50 mg/kg

Formal name: 2′-(3,4-dimethoxyphenyl)-6-(4-methylpiperazin-1-yl)-1H,3’H-2,5′-bibenzo[d]imidazole, trihydrochloride

Synonyms: 

Molecular weight: 577.9

CAS: 2095832-33-8

Purity: ≥98%

Formulation: A crystalline solid

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