An antiviral; prevents influenza nucleoprotein from accumulating in the nucleus; inhibits MDCK cell infection by influenza A and H5N1 (EC50s = 0.069 and 0.33 µM

Nucleozin – 50 mg

Brand:
Cayman
CAS:
341001-38-5
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Nucleozin is an antiviral inhibitor of influenza nucleoprotein accumulation, preventing it from translocating into the nucleus of host cells.{58045} It inhibits MDCK cell infection by influenza A and H5N1 (EC50s = 0.069 and 0.33 µM, respectively), as well as a clinical isolate of H3N2 (EC50 = 0.16 µM). Nucleozin reduces the lung viral load and increases the survival rate in a mouse model of influenza H5N1 infection.  

 

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SKU: 30363 - 50 mg Category:

Description

An antiviral; prevents influenza nucleoprotein from accumulating in the nucleus; inhibits MDCK cell infection by influenza A and H5N1 (EC50s = 0.069 and 0.33 µM, respectively), as well as a clinical isolate of H3N2 (EC50 = 0.16 µM); reduces the lung viral load and increases the survival rate in a mouse model of influenza H5N1 infection

Formal name: [4-(2-chloro-4-nitrophenyl)-1-piperazinyl](5-methyl-3-phenyl-4-isoxazolyl)-methanone

Synonyms: 

Molecular weight: 426.9

CAS: 341001-38-5

Purity: ≥98%

Formulation: A crystalline solid

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