Description
An antiosteoporotic agent; inhibits 1,25-dihydroxyvitamin D3-induced increases in the levels of carbonic anhydrase II and the vitronectin receptor, markers of osteoclast differentiation, in isolated chicken bone marrow cells at 0.1, 0.5, and 1 mM; pretreatment or continuous treatment of bovine bone slices at 1 mM inhibits bone resorption by isolated rat osteoclasts; decreases osteoclast surface and number but has no effect on the bone formation rate or mineral apposition rate in the alveolar bone in adult cynomolgus monkeys at 750 mg/kg per day
Formal name: 5-[bis(carboxymethyl)amino]-2-carboxy-4-cyano-3-thiopheneacetic acid, distrontium salt
Synonyms: S12911|S12911-2
Molecular weight: 513.5
CAS: 135459-87-9
Purity: ≥98%
Formulation: A crystalline solid
