Description
A phenylethanoid glycoside; active against E. coli, P. aeruginosa, and S. aureus (MICs = 38.33, 38.33, and 76.67 µg/ml, respectively); scavenges DPPH radicals (EC50 = 6.3 µg/ml); prevents Aβ (25-35)-induced apoptosis in PC12 cells at 10 and 25 µM; reduces cigarette smoke-induced increases in BALF levels of TNF-α, IL-6, and IL-1β and neutrophil and macrophage infiltration in a mouse model of COPD at 15, 30, and 60 mg/kg per day; decreases the latency mice take to find the platform in the Morris water maze in the SAMP8 model of rapid aging and dementia at 120 and 240 mg/kg per day
Formal name: 2-(3,4-dihydroxyphenyl)ethyl 6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-Glucopyranoside, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
Synonyms: Forsythiaside
Molecular weight: 624.6
CAS: 79916-77-1
Purity: ≥98%
Formulation: A crystalline solid
