Mer-NF5003F – 1 mg

Brand:
Cayman
CAS:
149598-70-9
Storage:
-20
UN-No:
Non-Hazardous - /

Mer-NF5003F is a sesquiterpene originally isolated from Stachybotrys with diverse biological activities.{46742,46743,46744} It inhibits avian myeloblastosis virus (AMV) protease (IC50 = 7.8 µM).{46742} Mer-NF5003F inhibits sialyltransferase 6N (ST6N), ST3O, and ST3N (IC50s = 0.61, 6.7, and 10 µg/ml, respectively), as well as fucosyltransferase (IC50 = 11.3 µg/ml).{46743} It is active against herpes simplex virus 1 (HSV-1) in vitro (IC50 = 4.32 µg/ml).{46744} Mer-NF5003F is also active against the multidrug-resistant P. falciparum strain K1 (IC50 = 0.85 µg/ml).  

 

Available on backorder

SKU: 29961 - 1 mg Category:

Description

A sesquiterpene with diverse biological activities; inhibits AMV protease (IC50 = 7.8 µM); inhibits ST6N , ST3O, and ST3N (IC50s = 0.61, 6.7, and 10 µg/ml, respectively), as well as fucosyltransferase (IC50 = 11.3 µg/ml); active against HSV-1 in vitro (IC50 = 4.32 µg/ml); active against the multidrug-resistant P. falciparum strain K1 (IC50 = 0.85 µg/ml)


Formal name: (1′R,2′R,4′aS,6′R,8′aS)-3′,4′,4′a,5′,6′,7′,8′,8′a-octahydro-4,6′-dihydroxy-2′,5′,5′,8′a-tetramethyl-spiro[benzofuran-2(3H),1′(2′H)-naphthalene]-6,7-dicarboxaldehyde

Synonyms:  F 1839M|NF 5003F|Stachybotrydial

Molecular weight: 386.5

CAS: 149598-70-9

Purity: ≥95%

Formulation: A solid