A meroditerpene fungal metabolite with diverse biological activities; inhibits the growth of MCF-7

Aszonapyrone A – 2.5 mg

Brand:
Cayman
CAS:
83103-08-6
Storage:
-20
UN-No:
Non-Hazardous - /

Aszonapyrone A is a meroditerpene fungal metabolite that has been found in Neosartorya and has diverse biological activities.{41303,41304,41720} It inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, and 10.2 μM, respectively).{41303} Aszonapyrone A is active against multidrug-resistant isolates of S. aureus, E. faecalis, and E. faecium (MICs = 8, 16, and 16 μg/ml, respectively) and inhibits S. aureus biofilm formation.{41304} It is also active against P. falciparum in vitro (IC50 = 1.34 μg/ml).{41720}  

 

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SKU: 29940 - 2.5 mg Category:

Description

A meroditerpene fungal metabolite with diverse biological activities; inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, and 10.2 μM, respectively); active against multidrug-resistant isolates of S. aureus, E. faecalis, and E. faecium (MICs = 8, 16, and 16 μg/ml, respectively) and inhibits S. aureus biofilm formation; active against P. falciparum in vitro (IC50 = 1.34 μg/ml)

Formal name: 3-[[(1R,4aS,4bR,7S,8aR,10aS)-7-(acetyloxy)tetradecahydro-4b,8,8,10a-tetramethyl-2-methylene-1-phenanthrenyl]methyl]-4-hydroxy-6-methyl-2H-pyran-2-one

Synonyms: 

Molecular weight: 456.6

CAS: 83103-08-6

Purity: ≥95%

Formulation: A solid

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