Description
A phenylethanoid glycoside; scavenges DPPH radicals (EC50 = 6.6 µM in a cell-free assay); inhibits hydrogen peroxide-induced production of ROS in a cell-free assay at 10 µg/ml; reduces increases in plasma ALT, TNF-α, IL-1β, IL-16, and IL-10 levels and hepatocyte apoptosis induced by LPS/D-galactosamine in a mouse model of acute liver injury at 60 mg/kg; prevents loss of dopaminergic neurons in the substantia nigra pars compacta and decreases in striatal dopamine and DOPAC levels in a mouse model of MPTP-induced Parkinson’s disease; improves motor performance in the rotarod test in the same model,,
Formal name: 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→6)]-β-D-glucopyranoside, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate]
Synonyms: trans-Acteoside|trans-Verbascoside|Kusaginin|NSC 603831
Molecular weight: 786.7
CAS: 82854-37-3
Purity: ≥95%
Formulation: A crystalline solid
