An oxadiazole antibiotic; is active against the Gram-positive bacteria S. aureus

CAY10742 – 5 mg

Brand:
Cayman
CAS:
1649473-91-5
Storage:
-20
UN-No:
Non-Hazardous - /

CAY10742 is an orally bioavailable oxadiazole antibiotic.{50791} It is active against the Gram-positive bacteria S. aureus, S. epidermidis, S. haemolyticus, B. cereus, B. licheniformis, E. faecalis, and E. faecium (MICs = 1-4 μg/ml), including laboratory strains and clinical isolates with varying degrees of resistance to methicillin, vancomycin, linezolid, and other antibiotics. CAY10742 (40 mg/kg) reduces the number of bacteria in mouse neutropenic thigh models of linezolid-sensitive or -resistant methicillin-resistant S. aureus (MRSA) infection.  

 

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SKU: 29800 - 5 mg Category:

Description

An oxadiazole antibiotic; is active against the Gram-positive bacteria S. aureus, S. epidermidis, S. haemolyticus, B. cereus, B. licheniformis, E. faecalis, and E. faecium (MICs = 1-4 μg/ml), including laboratory strains and clinical isolates with varying degrees of resistance to methicillin, vancomycin, linezolid, and other antibiotics; reduces the number of bacteria in mouse neutropenic thigh models of linezolid-sensitive or -resistant MRSA infection at 40 mg/kg

Formal name: 5-[3-[4-(4-fluorophenoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-indole

Synonyms: 

Molecular weight: 371.4

CAS: 1649473-91-5

Purity: ≥98%

Formulation: A crystalline solid

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