Eleutheroside E – 500 mg

Brand:
Cayman
CAS:
39432-56-9
Storage:
-20
UN-No:
Non-Hazardous - /

Eleutheroside E is a glycoside and major component of E. senticosus and has diverse biological activities.{46673} It protects against axonal and dendritic atrophies induced by amyloid-β (25-35) (Aβ (25-35); Item No. 24155) in primary rat cortical neurons.{46673,46675,46674,46676} Eleutheroside E (15, 30, and 60 mg/kg) reduces macrophage infiltration, pannus formation, cartilage damage, bone erosion, and the production of TNF-α and IL-6 in a mouse model of collagen-induced arthritis.{46675} It increases insulin sensitivity and reduces pancreatic α- and β-cell death in db/db diabetic mice.{46674} Eleutheroside E (10 and 50 mg/kg) increases the latency to enter the dark chamber in a passive avoidance test and the levels of glutathione (GSH) in the hippocampus and decreases errors in the Y-maze test and hippocampal malondialdehyde (MDA) levels in a mouse model of sleep deprivation-induced stress.{46676}  

 

Available on backorder

SKU: 29684 - 500 mg Category:

Description

A glycoside with diverse biological activities; protects against Aβ (25-35)-induced axonal and dendritic atrophies in primary rat cortical neurons; reduces macrophage infiltration, pannus formation, cartilage damage, bone erosion, and the production of TNF-α and IL-6 in a mouse model of collagen-induced arthritis at 15, 30, and 60 mg/kg; increases insulin sensitivity and reduces pancreatic α- and β-cell death in db/db mice; increases latency to enter the dark chamber in a passive avoidance test and hippocampal GSH levels and decreases errors in the Y-maze test and hippocampal MDA levels in a mouse model of sleep deprivation-induced stress at 10 and 50 mg/kg


Formal name: [(1R,3aR,4S,6aS)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(2,6-dimethoxy-4,1-phenylene)bis-β-D-glucopyranoside

Synonyms:  Syringin E

Molecular weight: 742.7

CAS: 39432-56-9

Purity: ≥95%

Formulation: A crystalline solid