An antifungal lipopeptide; active against C. albicans

FR901379 – 5 mg

Brand:
Cayman
CAS:
144371-88-0
Storage:
-20
UN-No:
Non-Hazardous - /

FR901379 is an echinocandin-like antifungal lipopeptide.{48802} It is active against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of pulmonary cysts and trophozoites in a mouse model of P. carinii infection.  

 

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SKU: 29648 - 5 mg Category:

Description

An antifungal lipopeptide; active against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = C. albicans infection in mice (ED50 = 1.1 mg/kg); reduces the number of pulmonary cysts and trophozoites in a mouse model of P. carinii infection

Formal name: 1-[(4R,5R)-4,5-dihydroxy-N2-(1-oxohexadecyl)-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]-pneumocandin A0

Synonyms: 

Molecular weight: 1,175.30

CAS: 144371-88-0

Purity: ≥90%

Formulation: A solid

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