An H1 receptor antagonist; induces histamine release in isolated guinea pig lung at 1 mM but completely prevents ovalbumin-induced histamine release in lungs isolated from ovalbumin-sensitized guinea pigs at 100 and 200 µg/ml; inhibits formalin-induced paw edema in rats at 17 mg/kg; increases survival in a mouse model of systemic S. typhimurium infection when administered at doses of 1.5 and 3 mg/kg

Bromodiphenhydramine (hydrochloride) – 10 mg

Brand:
Cayman
CAS:
1808-12-4
Storage:
-20
UN-No:
Non-Hazardous - /

Bromodiphenhydramine is a histamine H1 receptor antagonist.{46620} It induces histamine release in isolated guinea pig lung when used at a concentration of 1 mM but completely prevents ovalbumin-induced histamine release in lungs isolated from ovalbumin-sensitized guinea pigs when used at concentrations of 100 and 200 µg/ml.{46621} Bromodiphenhydramine (17 mg/kg) inhibits formalin-induced paw edema in rats.{46620} It increases survival in a mouse model of systemic S. typhimurium infection when administered at doses of 1.5 and 3 mg/kg.{46622}  

 

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SKU: 29636 - 10 mg Category:

Description

An H1 receptor antagonist; induces histamine release in isolated guinea pig lung at 1 mM but completely prevents ovalbumin-induced histamine release in lungs isolated from ovalbumin-sensitized guinea pigs at 100 and 200 µg/ml; inhibits formalin-induced paw edema in rats at 17 mg/kg; increases survival in a mouse model of systemic S. typhimurium infection when administered at doses of 1.5 and 3 mg/kg

Formal name: 2-[(4-bromophenyl)phenylmethoxy]-N,N-dimethyl-ethanamine, monohydrochloride

Synonyms:  Bromazine|NSC 36113

Molecular weight: 370.7

CAS: 1808-12-4

Purity: ≥98%

Formulation: A crystalline solid

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