A prodrug form of niflumic acid; decreases the rate of chloride/bicarbonate exchange in isolated mouse intestinal villous epithelial cells at 100 µM; dietary administration increases survival but has no effect on the number of crypt goblet cells in the jejunum or cecum in a cystic fibrosis mouse model of distal intestinal obstructive syndrome at 88 mg/kg

Talniflumate – 5 mg

Brand:
Cayman
CAS:
66898-62-2
Storage:
-20
UN-No:
- /

Talniflumate is a prodrug form of the COX-2 inhibitor niflumic acid (Item No. 70650).{53157} It decreases the rate of chloride/bicarbonate exchange by 55% in isolated mouse intestinal villous epithelial cells when used at a concentration of 100 µM.{53158} Dietary administration of talniflumate (88 mg/kg per day) increases survival but has no effect on the number of crypt goblet cells in the jejunum or cecum in a cystic fibrosis mouse model of distal intestinal obstructive syndrome.  

 

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SKU: 29623 - 5 mg Category:

Description

A prodrug form of niflumic acid; decreases the rate of chloride/bicarbonate exchange in isolated mouse intestinal villous epithelial cells at 100 µM; dietary administration increases survival but has no effect on the number of crypt goblet cells in the jejunum or cecum in a cystic fibrosis mouse model of distal intestinal obstructive syndrome at 88 mg/kg

Formal name: 2-[[3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester

Synonyms:  BA 7602-06

Molecular weight: 414.3

CAS: 66898-62-2

Purity: ≥95%

Formulation: A crystalline solid

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