A post-ganglionic sympathetic blocker; increases accumulation of l-m-octopamine in isolated rabbit heart at 1 mM; reduces norepinephrine levels in the left and right atrium and ventricles

Debrisoquin (hemisulfate) – 250 mg

Brand:
Cayman
CAS:
581-88-4
Storage:
-20
UN-No:
Non-Hazardous - /

Debrisoquin is a post-ganglionic sympathetic blocker.{52266} It increases accumulation of the monoamine oxidase (MAO) substrate l-m-octopamine in isolated rabbit heart when used at a concentration of 1 mM.{52267} Debrisoquin reduces norepinephrine levels in the left and right atrium and ventricles, as well as the mesenteric and femoral arteries in anesthetized dogs when administered at a dose of 5 mg/kg per day for seven days.{52268} Debrisoquin decreases mean aortic pressure, heart rate, and total peripheral vascular resistance in the same model.  

 

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SKU: 29568 - 250 mg Category:

Description

A post-ganglionic sympathetic blocker; increases accumulation of l-m-octopamine in isolated rabbit heart at 1 mM; reduces norepinephrine levels in the left and right atrium and ventricles, as well as the mesenteric and femoral arteries in anesthetized dogs at 5 mg/kg per day for 7 days; decreases mean aortic pressure, heart rate, and total peripheral vascular resistance in the same model.

Formal name: 3,4-dihydro-2(1H)-isoquinolinecarboximidamide, hemisulfate

Synonyms:  Isocaramidine sulfate|Ro 5-3307/1

Molecular weight: 224.3

CAS: 581-88-4

Purity: ≥98%

Formulation: A crystalline solid

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