A bacterial metabolite; active against a variety of bacteria

Urdamycin A – 1 mg

Brand:
Cayman
CAS:
98474-21-6
Storage:
-20
UN-No:
Non-Hazardous - /

Urdamycin A is a bacterial metabolite originally isolated from S. fradiae that has antibacterial and anticancer activities.{53476,53477} It is active against a variety of Gram-positive and Gram-negative bacteria, including B. subtilis and strains of Arthrobacter and Streptomyces, but not the fungus S. cerevisiae, in a disc assay when used at a concentration of 1 mg/ml.{53477} Urdamycin A is cytotoxic to L1210 and HT-29, but not A549, cancer cells (IC50s = 7.5, 5, and >10 µg/ml, respectively).{53476}  

 

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SKU: 29510 - 1 mg Category:

Description

A bacterial metabolite; active against a variety of bacteria, but not S. cerevisiae, at 1 mg/ml; cytotoxic to L1210 and HT-29, but not A549, cancer cells (IC50s = 7.5, 5, and >10 µg/ml, respectively)

Formal name: (3R,4aR,12bS)-9-[2,6-dideoxy-3-O-[(2S,5S,6S)-5-[(2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]-β-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3,4a,8-trihydroxy-3-methyl-12b-[[(2S,5S,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]oxy]-benz[a]anthracene-1,7,12(2H)-trione

Synonyms:  Antibiotic A 32Y2|Kerriamycin B|NSC 372208|NSC 606397

Molecular weight: 844.9

CAS: 98474-21-6

Purity: ≥70%

Formulation: A solid

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