An antimicrobial and radiosensitizer; active against T. vaginalis in a coulter counter antimicrobial assay (EC50 = 2.55 fmol/cell) and G. intestinalis (IC50 = 0.393 μM); reduces the number of vaginal trichomonads in a mouse model of T. vaginalis intravaginal infection (ED50 = 5.62 mg/kg); enhances radiation-induced SCC-7 tumor cell death in vitro and in vivo under hypoxic conditions

Nimorazole – 50 mg

Brand:
Cayman
CAS:
6506-37-2
Storage:
-20
UN-No:
Non-Hazardous - /

Nimorazole is 5-nitroimidazole with antimicrobial and radiosensitizing activities.{52125,52126,52128} It is active against T. vaginalis in a Coulter counter antimicrobial assay (EC50 = 2.55 fmol/cell) and G. intestinalis (IC50 = 0.393 μM).{52125,52126} Nimorazole reduces the number of vaginal trichomonads in a mouse model of T. vaginalis intravaginal infection (ED50 = 5.62 mg/kg).{52127} Under hypoxic conditions, nimorazole enhances radiation-induced SCC-7 tumor cell death in vitro and in vivo.{52128}  

 

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SKU: 29153 - 50 mg Category:

Description

An antimicrobial and radiosensitizer; active against T. vaginalis in a coulter counter antimicrobial assay (EC50 = 2.55 fmol/cell) and G. intestinalis (IC50 = 0.393 μM); reduces the number of vaginal trichomonads in a mouse model of T. vaginalis intravaginal infection (ED50 = 5.62 mg/kg); enhances radiation-induced SCC-7 tumor cell death in vitro and in vivo under hypoxic conditions

Formal name: 4-[2-(5-nitro-1H-imidazol-1-yl)ethyl]-morpholine

Synonyms:  Acterol|Naxofem|Naxogin|Nitrimidazine|NSC 107524

Molecular weight: 226.2

CAS: 6506-37-2

Purity: ≥95%

Formulation: A solid

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