A lipophilic fluorescent probe; rapidly incorporated into phospholipid cell membranes; has been used to label the plasma membrane and endocytic organelles in bovine aorta endothelial cells and rat hippocampal slices; has been used to assess proliferation in prostate cancer cell lines by flow cytometry; ex/em = 650/670 nm

DiD – 5 mg

Brand:
Cayman
CAS:
127274-91-3
Storage:
-20
UN-No:
Non-Hazardous - /

DiD is a lipophilic fluorescent probe.{47764} It is rapidly incorporated into phospholipid cell membranes and has been used to label the plasma membrane and endocytic organelles in bovine aorta endothelial cells and rat hippocampal slices.{47764,47765,47766} DiD has also been used to assess proliferation in prostate cancer cell lines by flow cytometry, where high DiD-expressing cell populations are associated with lower proliferation.{47764} DiD is not cytotoxic and can be detected in subcutaneously implanted PC3 cells in vivo after three weeks. It displays absorption/emission maxima of 650/670 nm, respectively.{47767}  

 

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SKU: 29115 - 5 mg Category:

Description

A lipophilic fluorescent probe; rapidly incorporated into phospholipid cell membranes; has been used to label the plasma membrane and endocytic organelles in bovine aorta endothelial cells and rat hippocampal slices; has been used to assess proliferation in prostate cancer cell lines by flow cytometry; ex/em = 650/670 nm, respectively

Formal name: 2-[5-(1,3-dihydro-3,3-dimethyl-1-octadecyl-2H-indol-2-ylidene)-1,3-pentadien-1-yl]-3,3-dimethyl-1-octadecyl-3H-indolium, monoperchlorate

Synonyms:  D 307|DiIC18(5)|NK 3175

Molecular weight: 959.9

CAS: 127274-91-3

Purity: ≥90%

Formulation: A crystalline solid

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