A stilbene with diverse biological activities; inhibits growth of A549

4′-O-Methylresveratrol – 10 mg

Brand:
Cayman
CAS:
33626-08-3
Storage:
-20
UN-No:
Non-Hazardous - /

4’-O-Methylresveratrol is a stilbene that has been found in Rumex and has diverse biological activities.{49468,49469,49470,49471} It inhibits growth of A549, SKOV3, SK-MEL-2, XF498, and HCT15 cancer cells (IC50s = 3.8, 5.7, 3.2, 5.6, and 6.7 µg/ml, respectively).{49468} 4’-O-Methylresveratrol (0.05-0.2 mM) inhibits rabbit platelet aggregation induced by collagen or arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607).{49469} It scavenges free radicals in a Trolox equivalent antioxidant capacity (TEAC) assay.{49470} 4’-O-Methyresveratrol suppresses RANKL-induced osteoclastic differentiation of murine bone marrow-derived macrophages (BMDMs) and reduces LPS-induced bone loss in mice when administered at a dose of 50 mg/kg.{49471}  

 

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SKU: 29106 - 10 mg Category:

Description

A stilbene with diverse biological activities; inhibits growth of A549, SKOV3, SK-MEL-2, XF498, and HCT15 cancer cells (IC50s = 3.8, 5.7, 3.2, 5.6, and 6.7 µg/ml, respectively); inhibits arachidonic acid- or collagen-induced rabbit platelet aggregation from 0.05-0.2 mM; scavenges free radicals in a TEAC assay; suppresses RANKL-induced osteoclastic differentiation of murine BMDMs; reduces LPS-induced bone loss in mice at 50 mg/kg

Formal name: 5-[(1E )-2-(4-methoxyphenyl)ethenyl]-1,3-benzenediol

Synonyms:  trans-3,5-Dihydroxy-4′-methoxystilbene|4-Methoxyresveratrol|Deoxyrhapontigenin

Molecular weight: 242.3

CAS: 33626-08-3

Purity: ≥98%

Formulation: A crystalline solid

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