Description
A saponin; prevents UVB-induced increases in ROS levels in HaCaT keratinocytes by 34.3, 54.4, and 65.4% when used at concentrations of 5, 12, and 30 µM, respectively; reduces increases in LPS-induced expression of Tnf, Il1b, and Ifnb1 in RAW 264.7 cells at 40 µg/ml; reduces gastric ulcer and joint lesion indices in mouse models of HCl/ethanol-induced gastritis and collagen-induced arthritis, respectively, as well as reduced increased serum levels of AST induced by LPS/D-galactosamine in a mouse model of hepatitis, at 20 mg/kg; increases GABA-induced inward current in Xenopus oocytes expressing recombinant human α1β1ɣ2S subunit-containing GABAA receptors (EC50 = 53.2 µM)
Formal name: (3β,12β)-20-[(6-O-α-L-arabinofuranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
Synonyms: NSC 310104|Panaxoside Rc
Molecular weight: 1,079.30
CAS: 11021-14-0
Purity: ≥98%
Formulation: A crystalline solid
