Description
A PDE5 inhibitor; increases penile ICP in rat models of STZ-induced diabetes and cavernosal nerve injury at 1 and 10 mg/kg, respectively; decreases bladder wall submucosal fibrosis and degeneration in a rat model of chronic bladder ischemia at 4 mg/kg per day; decreases bladder overactivity in a female rat model of partial bladder outlet obstruction
Formal name: 5-ethyl-3,5-dihydro-2-[5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]-2-propoxyphenyl]-7-propyl-4H-pyrrolo[3,2-d]pyrimidin-4-one, dihydrochloride
Synonyms: SK3530
Molecular weight: 604.6
CAS: 862189-96-6
Purity: ≥95%
Formulation: A crystalline solid