An undecapeptide tachykinin neuropeptide and NK receptor agonist; binds to NK1 (pD2 = 9.5 and 9.21 in isolated dog carotid artery and guinea pig ileum

Eledoisin – 10 mg

Brand:
Cayman
CAS:
69-25-0
Storage:
-20
UN-No:
Non-Hazardous - /

Eledoisin is an undecapeptide tachykinin neuropeptide and neurokinin (NK) receptor agonist originally isolated from E. moschata.{46470,46472} It binds to NK1 (pD2 = 9.5 and 9.21 in isolated dog carotid artery and guinea pig ileum, respectively), NK2 (pD2 = 8.22 and 7.7 in isolated rabbit pulmonary artery and rat duodenum, respectively), and NK3 receptors (pD2 = 7.11 and 7.06 in isolated rat portal vein and hamster urinary bladder, respectively).{46471} Eledoisin induces contraction of isolated guinea pig ileum and rabbit jejunum.{41381} It also induces salivation in rats and lowers arterial blood pressure in rabbits and guinea pigs in vivo.{41381,46473}  

 

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SKU: 28810 - 10 mg Category:

Description

An undecapeptide tachykinin neuropeptide and NK receptor agonist; binds to NK1 (pD2 = 9.5 and 9.21 in isolated dog carotid artery and guinea pig ileum, respectively), NK2 (pD2 = 8.22 and 7.7 in isolated rabbit pulmonary artery and rat duodenum, respectively), and NK3 (pD2 = 7.11 and 7.06 in isolated rat portal vein and hamster urinary bladder, respectively); induces contraction of isolated guinea pig ileum and rabbit jejunum; induces salivation in rats; lowers arterial blood pressure in rabbits and guinea pigs in vivo

Formal name: 5-oxo-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-α-aspartyl-L-alanyl-L-phenylalanyl-L-isoleucylglycyl-L-leucyl-L-methioninamide

Synonyms:  ELD 950|Moschatin

Molecular weight: 1,188.40

CAS: 69-25-0

Purity: ≥98%

Formulation: A crystalline solid

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