An anthocyanin; scavenges DPPH and ABTS radicals in cell-free assays (EC50s = 757 and 98 μM

Peonidin 3-O-glucoside (chloride) – 1 mg

Brand:
Cayman
CAS:
6906-39-4
Storage:
-20
UN-No:
Non-Hazardous - /

Peonidin 3-O-glucoside is a metabolite of cyanidin 3-glucoside (Item No. 16406) and an anthocyanin that has been found in red wine extracts and has diverse biological activities, including antioxidant, anti-inflammatory, antiproliferative, and anti-metastatic properties.{42980,42976,42977,42978,42979} Peonidin 3-O-glucoside scavenges 2,2-diphenyl 1-picylhydrazyl (DPPH; Item No. 14805) and ABTS (Item No. 27317) radicals in cell-free assays (EC50s = 757 and 98 μM, respectively).{42976} It inhibits IL-1β-induced phosphorylation of IKKα, IκBα, and ERK in human articular chondrocytes when used at a concentration of 2.5 μM.{42977} Peonidin 3-O-glucoside inhibits the growth of Hs578T human breast cancer cells in vitro in a concentration-dependent manner and decreases pulmonary metastasis in a mouse model of Lewis lung carcinoma when administered at a dose of 20 mg/kg.{42978,42979}  

 

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SKU: 28743 - 1 mg Category:

Description

An anthocyanin; scavenges DPPH and ABTS radicals in cell-free assays (EC50s = 757 and 98 μM, respectively); inhibits IL-1β-induced phosphorylation of IKKα, IκBα, and ERK in human articular chondrocytes at 2.5 μM; inhibits the growth of human Hs578T breast cancer cells in vitro in a concentration-dependent manner; decreases pulmonary metastasis in a mouse model of Lewis lung carcinoma at 20 mg/kg

Formal name: 3-(β-D-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-1-benzopyrylium, monochloride

Synonyms:  Peonidin 3-β-D-glucopyranoside

Molecular weight: 498.9

CAS: 6906-39-4

Purity: ≥95%

Formulation: A solid

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