An anticancer taxane; a precursor in the semisynthetic synthesis of paclitaxel; cytotoxic to KB carcinoma cells (EC50 = 0.027 μg/ml); reduces tumor growth in the PS mouse lymphocytic leukemia model at 16 mg/kg

10-deacetyl Paclitaxel – 5 mg

Brand:
Cayman
CAS:
78432-77-6
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

10-deacetyl Paclitaxel (10-DAP) is a taxane and precursor in the semisynthetic synthesis of paclitaxel (Item No. 10461) that has been found in Taxus and has anticancer activity.{47706,47707} It is cytotoxic to KB carcinoma cells (EC50 = 0.027 μg/ml).{47706} 10-DAP (16 mg/kg) reduces tumor growth in the PS mouse lymphocytic leukemia model.  

 

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SKU: 28503 - 5 mg Category:

Description

An anticancer taxane; a precursor in the semisynthetic synthesis of paclitaxel; cytotoxic to KB carcinoma cells (EC50 = 0.027 μg/ml); reduces tumor growth in the PS mouse lymphocytic leukemia model at 16 mg/kg

Formal name: (αR,βS)-β-(benzoylamino)-α-hydroxy-benzenepropanoic acid, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester

Synonyms:  10-DAP|10-Deacetyltaxol

Molecular weight: 811.9

CAS: 78432-77-6

Purity: ≥98%

Formulation: A solid

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