Description
A complex of the tripeptide Gly-His-Lys and a copper(II) ion that has wound healing and anti-inflammatory activities; increases proliferation and the levels of collagen and secreted pro-MMP-2 in isolated human fibroblasts at 1 nM; increases levels of collagen, GAGs, and the expression of decorin in the wound tissue of rats at 2 mg; decreases LPS-induced increases in levels of ROS, IL-6, and TNF-α in RAW 264.7 cells at 10 µM; prevents LPS-induced decreases in lung SOD activity and GSH levels and reduces LPS-induced increases in the number of cells and the level of total protein in BALF in a mouse model of acute lung injury
Formal name: [glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-copper, monoacetate
Synonyms: Gly-His-Lys-Cu(II)
Molecular weight: 462
CAS: 300801-03-0
Purity: ≥95%
Formulation: A solid
