A semi-synthetic tetracycline antibiotic; more active than tetracycline against 339 strains of anaerobic bacteria (MIC90s = 1 and 32 μg/ml

Sancycline (hydrochloride) – 100 mg

Brand:
Cayman
CAS:
6625-20-3
Storage:
-20
UN-No:
Non-Hazardous - /

Sancycline is a semi-synthetic tetracycline antibiotic that is more active than tetracycline (Item No. 14328) against 339 strains of anaerobic bacteria (average MIC90s = 1 and 32 μg/ml, respectively).{41112,41113} Sancycline is active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains with MICs ranging from 0.06 to 1 μg/ml.{41114} In vivo, sancycline is active against S. aureus in mice with ED50 values of 0.46 and 0.6 mg/kg for intravenous and subcutaneous administration, respectively.  

 

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SKU: 28118 - 100 mg Category:

Description

A semi-synthetic tetracycline antibiotic; more active than tetracycline against 339 strains of anaerobic bacteria (MIC90s = 1 and 32 μg/ml, respectively); active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains (MICs = 0.06-1 μg/ml); active against S. aureus in mice (ED50s = 0.46 and 0.6 mg/kg for intravenous and subcutaneous administration, respectively)

Formal name: (4S,4aS,5aR,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide, monohydrochloride

Synonyms:  6-Demethyl-6-deoxytetracycline|NSC 51812

Molecular weight: 450.9

CAS: 6625-20-3

Purity: ≥95%

Formulation: A crystalline solid

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