A sesquiterpene with antibiotic and anticancer activities; active against S. aureus

Terrecyclic Acid – 1 mg

Brand:
Cayman
CAS:
83058-94-0
Storage:
-20
UN-No:
Non-Hazardous - /

Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity.{46285} It is active against S. aureus, B. subtilis, and M. roseus (MICs = 25, 50, and 25 μg/ml, respectively). Terrecyclic acid induces a heat shock response, increases levels of reactive oxygen species (ROS), and inhibits NF-κB activity and cell growth in 3T3-Y9-B12 cells.{46286} In vivo, terrecyclic acid (0.1, 1, and 10 mg/ml) reduces the number of ascitic fluid tumor cells in a mouse model of P388 murine leukemia.{46285}  

 

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SKU: 28117 - 1 mg Category:

Description

A sesquiterpene with antibiotic and anticancer activities; active against S. aureus, B. subtilis, and M. roseus (MICs = 25, 50, and 25 μg/ml, respectively); induces a heat shock response, increases levels of ROS, and inhibits NF-κB activity and cell growth in 3T3-Y9-B12 cells; reduces the number of ascitic fluid tumor cells in a mouse model of P388 murine leukemia at 0.1, 1, and 10 mg/ml

Formal name: (3aS,4R,7R,7aR)-octahydro-8,8-dimethyl-3-methylene-2-oxo-3a,7-ethano-3aH-indene-4-carboxylic acid

Synonyms: 

Molecular weight: 248.3

CAS: 83058-94-0

Purity: ≥95%

Formulation: A solid

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