Description
A δ lactone with anticancer activity; cytotoxic to adriamycin-susceptible P388, T-24, HeLa, A549, and HL-60 cancer cells (IC50s = 4, 0.5, 1, 1, and 0.2 µg/ml, respectively), as well as adriamycin-resistant HL-60/ADR cells (IC50 = 0.1 µg/ml); inhibits DNA, RNA, and protein synthesis in HeLa cells (IC50 = 1.25 µg/ml for all)
Formal name: (2R,3R,7S,7aR)-2,3,7,7a-tetrahydro-3-hydroxy-2,7-di-(1E)-1-propen-1-yl-5H-furo[3,4-b]pyran-5-one
Synonyms: (–)-Waol A
Molecular weight: 236.3
CAS: 162341-24-4
Purity: ≥70%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Cancer||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis
