A phenolic stilbene glucoside with antioxidant and antineoplastic activities; scavenges DPPH radicals (IC50 = 30.2 μM) in a cell-free assay and inhibits cupric ion-induced lipid peroxidation of human LDL (IC50 = 3 μM); inhibits development of DMBA-induced preneoplastic lesions in mouse mammary gland organ cultures by 68.8% at 10 µg/ml

Astringin – 1 mg

Brand:
Cayman
CAS:
29884-49-9
Storage:
-20
UN-No:
Non-Hazardous - /

Astringin is a phenolic stilbene glucoside that has been found in V. vinifera and has antioxidant and antineoplastic activities.{50296,50297} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals (IC50 = 30.2 μM) in a cell-free assay and inhibits cupric ion-induced lipid peroxidation of human LDL (IC50 = 3 μM).{50296} Astringin (10 µg/ml) inhibits development of preneoplastic lesions induced by 7,12-dimethylbenz(a)anthracene (DMBA) in mouse mammary gland organ cultures by 68.8%.{50297}  

 

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SKU: 27979 - 1 mg Category:

Description

A phenolic stilbene glucoside with antioxidant and antineoplastic activities; scavenges DPPH radicals (IC50 = 30.2 μM) in a cell-free assay and inhibits cupric ion-induced lipid peroxidation of human LDL (IC50 = 3 μM); inhibits development of DMBA-induced preneoplastic lesions in mouse mammary gland organ cultures by 68.8% at 10 µg/ml

Formal name: 3-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-5-hydroxyphenyl β-D-glucopyranoside

Synonyms:  (E)-Astringin|trans-Astringin|3,4,3′,5′-Tetrahydroxystilbene 3′-glucoside

Molecular weight: 406.4

CAS: 29884-49-9

Purity: ≥90%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Glycosides||Product Type|Biochemicals|Natural Products|Polyphenols||Product Type|Biochemicals|Natural Products|Stilbenes||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic

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