An imidazole antifungal agent; inhibits the growth of clinical isolates of C. albicans (MIC = 0.29 μg/ml)

(±)-Climbazole – 25 g

Brand:
Cayman
CAS:
38083-17-9
Storage:
-20
UN-No:
Non-Hazardous - /

(±)-Climbazole is an imidazole antifungal agent.{47625} It inhibits the growth of C. albicans (MIC = 0.29 μg/ml), as well as clinical isolates of M. pachydermatis (MICs = M. furfur (MICs = in vitro.{48240,48241,47626} It also reduces the size of Malassezia populations on the skin of naturally infected dogs when used at a dose of 2% in shampoo.{47625} (±)-Climbazole (80 mg/kg) increases the levels of cytochrome P450 in rat liver.{48242} Formulations containing climbazole have been used in the treatment of dandruff.  

 

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SKU: 27968 - 25 g Category:

Description

An imidazole antifungal agent; inhibits the growth of clinical isolates of C. albicans (MIC = 0.29 μg/ml), as well as M. pachydermatis (MICs = M. furfur (MBCs = Malassezia populations on the skin of naturally infected dogs at 2% in shampoo; increases the levels of cytochrome P450 in rat liver at 80 mg/kg

Formal name: 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl-2-butanone

Synonyms:  BAY-e 6975

Molecular weight: 292.8

CAS: 38083-17-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antifungals|Imidazoles||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Fungal Diseases|Candidiasis

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