An active metabolite of iloperidone; binds to 5-HT1B

Iloperidone metabolite P88 – 5 mg

Brand:
Cayman
CAS:
133454-55-4
Storage:
-20
UN-No:
Non-Hazardous - /

Iloperidone metabolite P88 is an active metabolite of the atypical antipsychotic iloperidone (Item No. 22957).{43847,43848} It binds to the serotonin (5-HT) receptor subtypes 5-HT1B, 5-HT2A, and 5-HT2C (Kis = 5.1, 0.03, and 6.9 nM, respectively), α2b- and α2c-adrenergic (Kis = 6 and 1.3 nM, respectively), and dopamine D1, D2A, and D4 receptors (Kis = 9.5, 1.6, and 3.5 nM, respectively).{43847}  

 

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SKU: 27806 - 5 mg Category:

Description

An active metabolite of iloperidone; binds to 5-HT1B, 5-HT2A, and 5-HT2C (Kis = 5.1, 0.03, and 6.9 nM, respectively), α2b- and α2c-adrenergic (Kis = 6 and 1.3 nM, respectively), and dopamine D1, D2A, and D4 receptors (Kis = 9.5, 1.6, and 3.5 nM, respectively)

Formal name: 4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxy-α-methyl-benzenemethanol

Synonyms:  P88-8991

Molecular weight: 428.5

CAS: 133454-55-4

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Receptor Pharmacology||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Neuroscience|Behavioral Neuroscience|Anxiety||Research Area|Neuroscience|Behavioral Neuroscience|Schizophrenia & Psychosis

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