A fluorescent probe for peptide labeling commonly used in the study of proteases; conjugation via its amino group to a peptide substrate results in quenching of the fluorescent signal; upon enzymatic cleavage of the peptide by proteases

7-Amino-4-methylcoumarin – 1 g

Brand:
Cayman
CAS:
26093-31-2
Storage:
-20
UN-No:
Non-Hazardous - /

7-Amino-4-methylcoumarin (AMC) is a fluorescent probe for peptide labeling commonly used in the study of proteases.{38188,43579,41518} Conjugation of AMC via its amino group to a peptide substrate results in quenching of the fluorescent signal.{38188} Upon enzymatic cleavage of the peptide by proteases, AMC is released and its fluorescence can be used to quantify enzyme activity. AMC displays excitation/emission maxima of 345/445 nm, respectively.{45292}  

 

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SKU: 27792 - 1 g Category:

Description

A fluorescent probe for peptide labeling commonly used in the study of proteases; conjugation via its amino group to a peptide substrate results in quenching of the fluorescent signal; upon enzymatic cleavage of the peptide by proteases, AMC is released and its fluorescence can be used to quantify enzyme activity; ex/em = 345/445 nm, respectively

Formal name: 7-amino-4-methyl-2H-1-benzopyran-2-one

Synonyms:  4-methyl-7-aminocoumarin|AMC|Coumarin 120|NSC 45796

Molecular weight: 175.2

CAS: 26093-31-2

Purity: ≥98%

Formulation: A solid

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Product Type|Biochemicals|Labeling & Detection|Reactive Probes||Research Area|Cell Biology|Proteolysis

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