A BET bromodomain inhibitor; decreases c-Myc expression and induces cancer cell death in c-Myc-driven cancer cell lines in vitro; inhibits tumor growth in triple-negative breast

BMS 986158 – 5 mg

Brand:
Cayman
CAS:
1800340-40-2
Storage:
-20
UN-No:
Non-Hazardous - /

BMS 986158 is a BET bromodomain inhibitor with anticancer activity.{46357} It decreases c-Myc expression and induces cancer cell death in c-Myc-driven cancer cell lines in vitro. BMS 986158 inhibits tumor growth in triple-negative breast, colorectal, and lung cancer patient-derived mouse xenograft models.  

 

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SKU: 27789 - 5 mg Category:

Description

A BET bromodomain inhibitor; decreases c-Myc expression and induces cancer cell death in c-Myc-driven cancer cell lines in vitro; inhibits tumor growth in triple-negative breast, colorectal, and lung cancer patient-derived mouse xenograft models

Formal name: 3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-α,α-dimethyl-5-[(S)-phenyl(tetrahydro-2H-pyran-4-yl)methyl]-5H-pyrido[3,2-b]indole-7-methanol

Synonyms: 

Molecular weight: 495.6

CAS: 1800340-40-2

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Small Molecule Inhibitors|Chromatin Reader Interactions||Research Area|Cancer|Transcription Factors||Research Area|Epigenetics, Transcription, & Translation|Readers|Bromodomains

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