An active metabolite of tryptophan; inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%

3-hydroxy-DL-Kynurenine – 10 mg

Brand:
Cayman
CAS:
484-78-6
Storage:
-20
UN-No:
Non-Hazardous - /

3-hydroxy-DL-Kynurenine is an active metabolite of tryptophan.{42852,42853,42854} It inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%, respectively, when used at a concentration of 100 μM.{42852} 3-hydroxy-DL-Kynurenine is active against methicillin-resistant S. aureus (MRSA), S. epidermidis, vancomycin-resistant E. faecalis (VRE), E. coli, multidrug-resistant P. aeruginosa (MDRP), and C. albicans (IC50s = 31.2, 39.2, 57.6, 24, 25.6, and 137.6 μg/ml, respectively).{42853} It increases intracellular NAD+ levels and extracellular lactate dehydrogenase (LDH) activity in human neurons and astrocytes in a concentration-dependent manner.{42854}  

 

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SKU: 27778 - 10 mg Category:

Description

An active metabolite of tryptophan; inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%, respectively, at 100 μM; active against MRSA, S. epidermidis, VRE, E. coli, MDRP, and C. albicans (IC50s = 31.2, 39.2, 57.6, 24, 25.6, and 137.6 μg/ml, respectively); increases intracellular NAD+ levels and extracellular LDH activity in human neurons and astrocytes ,

Formal name: α,2-diamino-3-hydroxy-γ-oxo-benzenebutanoic acid

Synonyms:  3-Hydroxykynurenine|DL-3-Hydroxykynurenine

Molecular weight: 224.2

CAS: 484-78-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|MRSA||Research Area|Infectious Disease|Fungal Diseases|Candidiasis||Research Area|Neuroscience

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