Aspergillimide – 5 mg

Brand:
Cayman
CAS:
195966-93-9
Storage:
-20
UN-No:
Non-Hazardous - /

Aspergillimide is a fungal metabolite originally isolated from A. japonicus.{42741} It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons (IC50s = 20.2 and 39.6 nM, respectively) but has no effect on chicken α3β4-, α4β2-, and α7-containing nAChRs.{42742} Dietary administration of aspergillimide A (10 µg/g of diet) induces paralysis in silkworm fourth instar larvae.{42741} Aspergillimide A (10 and 20 mg/kg) reduces T. colubriformis fecal egg count in gerbils.{46107}  

 

Available on backorder

SKU: 27738 - 5 mg Category:

Description

A fungal metabolite; reduces nAChR peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm larval neurons (IC50s = 20.2 and 39.6 nM, respectively); dietary administration induces paralysis in silkworm fourth instar larvae at 10 µg/g of diet; reduces T. colubriformis fecal egg count in gerbils at 10 and 20 mg/kg ,


Formal name: (1R,3’R,5aR,8aR,9aS)-rel-(-)-tetrahydro-1,1′,8,8,11-pentamethyl-spiro[5H,6H-5a,9a-(iminomethano)-1H-cyclopent[f]indolizine-7(8H),3′-pyrrolidine]-2′,5′,10-trione

Synonyms:  Asperparaline A|VM 55598

Molecular weight: 359.5

CAS: 195966-93-9

Purity: ≥98%

Formulation: A solid


Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases||Research Area|Neuroscience