An alkaloid fungal metabolite; inhibits cell death induced by influenza A strain A/PR/8/34 in MDCK cells (IC50 = 10 μg/ml); inhibits viral replication in a plaque assay in a concentration-dependent manner; inhibits ADP and PAF-induced platelet aggregation in vitro (IC50s = 180 and 240 μM

Herquline A – 1 mg

Brand:
Cayman
CAS:
71812-08-3
Storage:
-20
UN-No:
Non-Hazardous - /

Herquline A is an alkaloid fungal metabolite originally isolated from P. herquei.{42744} It inhibits cell death induced by influenza A strain A/PR/8/34 in MDCK cells with an IC50 value of 10 μg/ml and inhibits viral replication in a plaque assay in a concentration-dependent manner.{42745} Herquline A also inhibits platelet aggregation induced by ADP (Item No. 16778) and platelet-activating factor (PAF) in vitro (IC50s = 180 and 240 μM, respectively).{42744}  

 

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SKU: 27731 - 1 mg Category:

Description

An alkaloid fungal metabolite; inhibits cell death induced by influenza A strain A/PR/8/34 in MDCK cells (IC50 = 10 μg/ml); inhibits viral replication in a plaque assay in a concentration-dependent manner; inhibits ADP and PAF-induced platelet aggregation in vitro (IC50s = 180 and 240 μM, respectively)

Formal name: (2R,5R,11S,11aS,14aS,14bR)-rel-(-)-1,2,5,6,8,9,11,11a,13,14,14a,14b-dodecahydro-16-methyl-4H-5,2-(iminomethano)-11,7-methenopyrrolo[3,2,1-no][1]benzazacycloundecine-10,12-dione

Synonyms: 

Molecular weight: 314.4

CAS: 71812-08-3

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Natural Products|Alkaloids||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|Influenza

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