A triterpenoid; an inhibitor of β-glucuronidase (IC50 = 0.12 mg/ml in rat liver microsomes); reduces increases in serum AST

Ganoderenic Acid A – 10 mg

Brand:
Cayman
CAS:
100665-40-5
Storage:
-20
UN-No:
Non-Hazardous - /

Ganoderenic acid A is a triterpenoid originally isolated from G. lucidum that has enzyme inhibitory activities.{48894,48895,48896} It is an inhibitor of β-glucuronidase (IC50 = 0.12 mg/ml in rat liver microsomes).{48895} Ganoderenic acid A (100 mg/kg) reduces increases in serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) in a rat model of liver injury induced by carbon tetrachloride (CCl4). It also inhibits aldose reductase by 54.2% when used at a concentration of 100 µg/ml.{48896}  

 

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SKU: 27685 - 10 mg Category:

Description

A triterpenoid; an inhibitor of β-glucuronidase (IC50 = 0.12 mg/ml in rat liver microsomes); reduces increases in serum AST, ALT, and LDH in a CCl4-induced rat model of liver injury at 100 mg/kg; inhibits aldose reductase by 54.2% at 100 µg/ml

Formal name: (7β,15α,20E)-7,15-dihydroxy-3,11,23-trioxo-lanosta-8,20(22)-dien-26-oic acid

Synonyms: 

Molecular weight: 514.7

CAS: 100665-40-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Natural Products|Terpenes||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Endocrinology & Metabolism|Carbohydrate Metabolism

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