An anthracycline with anticancer activity; cytotoxic to MCF-7 and K562 cells (IC50s = 90 and 60 nM

Carubicin – 1 mg

Brand:
Cayman
CAS:
50935-04-1
Storage:
-20
UN-No:
Non-Hazardous - /

Carubicin is an anthracycline originally isolated from A. carminata that has anticancer activity.{46527,46528} It is cytotoxic to MCF-7 and K562 cells (IC50s = 90 and 60 nM, respectively), as well as P-glycoprotein-expressing MCF-7/DOX and K562i/S9 cells (IC50s = 90 and 60 nM, respectively).{46527}  

 

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SKU: 27660 - 1 mg Category:

Description

An anthracycline with anticancer activity; cytotoxic to MCF-7 and K562 cells (IC50s = 90 and 60 nM, respectively), as well as P-glycoprotein-expressing MCF-7/DOX and K562i/S9 cells (IC50s = 90 and 60 nM, respectively)

Formal name: (8S,10S)-8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-5,12-naphthacenedione

Synonyms:  Antibiotic R 588A|Carminomycin|NCI 180024|NSC 180024

Molecular weight: 513.5

CAS: 50935-04-1

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Cancer|Cell Death||Research Area|Cancer|Multidrug Resistance

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